Hypomethylation of DNA during differentiation of friend erythroleukemia cells
نویسندگان
چکیده
منابع مشابه
Hypomethylation of DNA during differentiation of friend erythroleukemia cells
DNA from mammalian cells has been shown to contain significant amounts of 5-methyl cytosine resulting from enzymatic transfer of methyl groups from s-adenosylmethionine to cytosine residues in the DNA polymer. The function of this modification is not known. We have found that DNA synthesized during chemically induced differentiation of friend erythroleukemia cells is hypomethylated, as measured...
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Cholesterol is an essential constituent of all mammalian cell membranes and its availability is therefore a prerequisite for cellular growth and other functions. Several lines of evidence are now indicating an association between alterations of cholesterol homeostasis and cell cycle progression. However, the role of cholesterol in cell differentiation is still largely unknown. To begin to addre...
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ژورنال
عنوان ژورنال: Journal of Cell Biology
سال: 1980
ISSN: 1540-8140,0021-9525
DOI: 10.1083/jcb.86.2.366